Stage 0: At this stage, there are no risk factors for CKM, and the goal is to prevent CKM syndrome (incredibly unhealthy weight gain) by achieving and maintaining a healthy lifestyle.
Stage 1: At this stage, there is overweight, abdominal obesity, or fat tissue dysfunction (clinically manifested by impaired glucose tolerance or a prediabetic state) without other metabolic risk factors for cardiovascular diseases (CVD).
Stage 2: At this stage, metabolic risk factors are present (hypertriglyceridemia, hypertension, metabolic syndrome, diabetes) and kidney diseases. The goal is to manage risk factors to prevent progression to CVD and kidney failure.
Stage 3: This stage describes individuals with subclinical CVD with metabolic risk factors or kidney disease or those at high predicted risk of CVD.
Stage 4: Individuals with CKM syndrome at stage 4 have symptomatic CVD, excess fat tissue, metabolic risk factors, or kidney disease.
Based on: https://doi.org/10.1161/CIR.0000000000001184